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Author SHA1 Message Date
wangjinlei
2b173cb0a2 1 2026-02-11 16:53:58 +08:00
wangjinlei
6c5d8b874f 1 2026-02-11 16:53:33 +08:00
7 changed files with 1648 additions and 1505 deletions
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article_3113.aux
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article_3113.tex
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@@ -13,6 +13,7 @@ page=57,%号
\journalweb{https://www.tmrjournals.com/tmr}
\usepackage{amsmath}
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@@ -22,6 +23,10 @@ page=57,%号
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\setlength{\parindent}{1em}%缩进大小
\title{Natural flavonoids for the treatment of chronic obstructive pulmonary disease: An overview}
\author{Peng-Liang Shi}
@@ -83,6 +88,7 @@ Natural products are still a crucial source for drug screening and discovery bec
\par
\section{\textit{\textbf{Pathogenesis of COPD}}}
\par
COPD is a progressive respiratory condition defined by significant airflow limitation, mucus overproduction, chronic bronchitis, emphysema, or damage to the alveolar septal walls. These manifestations lead to symptoms such as wheezing, coughing, and dyspnea, which can result in acute exacerbations, hospitalisation, and even death \parencite{ref_132735}.\par
CS, pathogens, and various environmental exposures are significant external risk factors contributing to the development of COPD; notably, the removal of these risk factors has the potential to halt the pathological progression of the disease \textcolor[HTML]{0082AA}{[4, 15]}. Other factors, including genetics, gender, occupation, airway hyperresponsiveness, lung growth and development, and infections, also significantly contribute to the pathogenesis of COPD \parencite{ref_132735,ref_132736,ref_132737}. COPD is characterised by persistent inflammation and fibrosis of the small airways and the deterioration of lung parenchyma, also known as emphysema \textcolor[HTML]{0082AA}{[18, 19]}. COPD is complicatedly regulated by various biological mechanisms and their crosstalk, including oxidative stress, inflammation, ECM homeostasis, apoptosis, pyroptosis, and mucous cell hyperplasia \textcolor[HTML]{0082AA}{[7, 20-24]}. Among these, the regulation mechanism of oxidative stress and inflammation has attracted much attention in the field of COPD research and drug discovery, and airway remodelling and fibrosis are critical pathological features of late-stage COPD.\par
\par
@@ -200,11 +206,15 @@ COPD, chronic obstructive pulmonary disease; CS, cigarette smoke; ROS, reactive
\textit{\textbf{Citation}}\par
Shi PL, Zhang GX, Wang PY, Liu ZQ, Zheng BQ. Natural flavonoids for the treatment of chronic obstructive pulmonary disease: An overview. \textit{Tradit Med Res}. 2025;10(9):57. doi: 10.53388/TMR20241121001.\par
\par
\begin{figure*}[!htbp]
\centering
\includegraphics[width=0.9\textwidth]{./image/zipimg67aea6fbb71406.png}
\end{figure*}\par
\textbf{Executive editor: }Xin-Yue Zhang.\par
\textbf{Received: }22 November 2024; \textbf{Revised:} 01 January 2025; \textbf{Accepted: }27 February 2025; \textbf{Available online:} 03 March 2025.\par
© 2025 By Author(s). Published by TMR Publishing Group Limited. This is an open access article under the CC-BY license. (https://creativecommons.org/licenses/by/4.0/)\par
\FloatBarrier
\nocite{*}
\printbibliography[title={References}]

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tmr-tex.cls
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%Author contributions
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